Explore Advanced Allergy Solutions
Discover the Power of Immunotherapy
Unlock a healthier life with cutting-edge immunotherapy treatments designed to tackle allergies at their root. Learn about our specialized approaches, including sublingual immunotherapy (SLIT), and how they can transform your allergy management.
Understanding Immunotherapy

At Great British Allergy Clinic, we provide specialist allergen immunotherapy for adults and children suffering from persistent allergic conditions such as hay fever, house dust mite allergy, pollen allergy, animal allergy, and selected venom allergies. Immunotherapy is an evidence-based treatment recognised by international allergy organisations, including the European Academy of Allergy and Clinical Immunology (EAACI) and the British Society for Allergy & Clinical Immunology (BSACI), as the only allergy treatment capable of modifying the underlying immune response to allergens rather than simply masking symptoms.
Allergen immunotherapy works by gradually exposing the immune system to carefully controlled amounts of a specific allergen over time. This controlled exposure helps the immune system become less reactive and develop long-term tolerance to the allergen. As treatment progresses, many patients experience a significant reduction in allergy symptoms, decreased reliance on antihistamines and other medications, and an improvement in overall quality of life. Clinical studies have also shown that immunotherapy may help reduce the risk of progression from allergic rhinitis to asthma in some patients and may provide lasting benefits even after treatment has been completed.
Immunotherapy may be recommended for patients with moderate to severe allergies that are not adequately controlled with standard medication or allergen avoidance measures. It is commonly used for seasonal allergic rhinitis (hay fever), dust mite allergy, grass and tree pollen allergy, pet allergy, and insect venom allergy (as injections). Depending on the patient’s condition and allergy profile, respiratory allergy treatment may be administered as sublingual immunotherapy (SLIT), which is taken under the tongue.
At Great British Allergy Clinic, every immunotherapy treatment plan is tailored to the individual patient following a comprehensive allergy assessment and advanced diagnostic testing. Our consultant-led approach ensures that treatment is personalised according to the patient’s medical history, allergy triggers, lifestyle, symptom severity, and long-term health goals. We use evidence-based protocols and carefully monitored treatment schedules to maximise both safety and effectiveness.
Our clinic offers comprehensive support throughout the immunotherapy journey, including specialist consultations, allergy testing, treatment initiation, ongoing monitoring, and long-term follow-up care. We are dedicated to helping patients achieve better symptom control, improved daily functioning, and long-term relief from allergic disease through modern personalised allergy care.
Immunotherapy Options
Sublingual Immunotherapy (SLIT)
SLIT is a convenient, evidence-based allergy treatment that involves placing carefully measured allergen extracts under the tongue on a regular basis. SLIT is widely used for conditions such as hay fever, grass pollen allergy, tree pollen allergy, and house dust mite allergy. The treatment works by gradually training the immune system to become less sensitive to specific allergens, helping to reduce allergic inflammation and improve long-term symptom control.
Clinical studies have shown that SLIT may significantly reduce allergy symptoms, and improve overall quality of life.
SLIT is considered a disease-modifying treatment because it targets the underlying allergic response rather than simply relieving symptoms temporarily.
Subcutaneous Immunotherapy (SCIT)
SCIT is commonly known as allergy shots, involves regular injections of allergens to build tolerance over time. This method is highly effective for severe allergies and is administered under medical supervision in the hospital setting. Since COVID pandemic this treatment is used less as more convenient SLIT came to its place offering a non-invasive and generally well-tolerated alternative for many patients. SLIT after the initial consultant supervised dose, treatment is usually continued at home, making it particularly convenient for adults and children requiring long-term allergy management.
At Great British Allergy Clinic, all SLIT treatment plans are personalised following specialist allergy assessment and diagnostic testing to ensure safe, effective, and evidence-based care tailored to each patient’s needs.
Venom Immunotherapy (VIT)
VIT is a highly effective specialist treatment designed for individuals with severe allergic reactions to insect stings, in the UK bee and wasp venom allergy. It is considered one of the most successful forms of allergen immunotherapy, with protection rates approaching 90–98% for preventing serious systemic allergic reactions following future stings. It must be performed in an appropriately equipped specialist hospital with trained medical supervision and emergency support available.
Venom immunotherapy is recommended for patients with a history of moderate to severe systemic reactions to bee or wasp stings and confirmed venom allergy through specialist diagnostic testing.
Understanding Sublingual Immunotherapy

Benefits of Sublingual Immunotherapy
At Great British Allergy Clinic, all SLIT treatment plans are personalised following comprehensive allergy assessment and diagnostic testing. Our consultant-led approach ensures safe, evidence-based, and individually tailored allergy care. SLIT is an evidence-based allergy treatment designed to gradually reduce the immune system’s sensitivity to specific allergens over time. Commonly used for hay fever, rass and tree gpollen allergy, and house dust mite allergy, SLIT works by administering carefully controlled allergen extracts under the tongue, helping the immune system develop long-term tolerance and reducing allergic inflammation.
Common Questions About SLIT
Explore answers to the most frequently asked questions about sublingual immunotherapy and how it can help manage allergies effectively.
What is Sublingual Immunotherapy?
Sublingual Immunotherapy (SLIT) is a treatment for allergies where small doses of allergens are placed under the tongue, helping the immune system build tolerance and reduce symptoms over time.
How long does SLIT treatment take?
SLIT treatment typically lasts three to five years. Patients often notice symptom improvement within the first few months, with continued benefits throughout the treatment duration.
Are there any side effects of SLIT?
SLIT is generally well-tolerated. Some patients may experience mild side effects such as itching or tingling in the mouth, but these usually resolve quickly.

Schedule Your Consultation Today
Ready to take control of your allergies? Contact us to learn more about our innovative sublingual immunotherapy options and how they can help you achieve lasting relief. Our specialists are here to guide you through every step of your treatment journey.
